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Darie Nani

Darie Nani

Editor-in-Chief·Founder, Sovereign Magazine

Aiming to inform, educate and sometimes amuse.

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Articles by Darie Nani(99)

The treatment room at Esthetics By Kyrsta in North Canton, Ohio, with the facial bed, product shelves and equipment trolleyEveryday Wellness

Former LA Makeup Artist Kyrsta Morehouse Brings a Non-Surgical Facelift to North Canton

At her one-person studio, Esthetics By Kyrsta, she combines facial cupping, microcurrent and contrast therapy in one treatment, and says 85% of her clients now rebook.

·4 min read
A clinician in scrubs holds a patient's hand in both of hers against a white background.Health

An Experimental Drug for a Fast-Moving Genetic ALS Meets Its Goal in a Global Trial

FUS-ALS, the rare and often young-onset form of the disease, has never had a treatment made for it, and the FUSION trial is the first real evidence that one could be coming.

·3 min read
Elizabeth M. Lykins, author and spiritual coachMental Health, Everyday Wellness

Physician Associate and Spiritual Coach Elizabeth M. Lykins Says Lasting Change Begins in Stillness

An urgent care provider since 1996, Elizabeth wrote Reflections on Transcendence, which features 59 paintings by her lifelong friend, the late expressionist Steven D. Lyons, who selected each painting to match the text.

·6 min read
Two researchers in white lab coats at work in a biomedical laboratory, one at a microscope and one at a fume hoodscience & tech
Members

Two Child Deaths in China's Gene-Editing Trials Went Undisclosed for More Than a Year

The viral vector reaction that killed both children is a known hazard of gene therapy; what was new was the silence around the cases and China's rules, which carry no requirement to make trial deaths public.

·1 min read
Two researchers working at benches in a laboratoryLongevity & Science

An FDA-Cleared Trial Will Test Engineered Immune Cells Against Advanced Colorectal Cancer

The same class of therapy that clears some blood cancers has almost never worked against solid tumors, and this first-in-human study is designed to test safety, not to prove it works.

·3 min read
Researchers in a conference room reviewing a colour-coded spleen scan on a wall screenLongevity & Science
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AI Study Links Hidden Spleen Features to Higher Heart Disease Risk

The link, drawn from AI reading of abdominal scans in more than 42,000 people, points to what researchers call a heart-spleen axis behind risk that cholesterol control does not explain. It is early science, and the pattern did not hold up when tested in everyday patients.

·1 min read
Illustration of a DNA double helix with a glowing central strand, representing protection of the genomeLongevity & Science

Eating Fewer Calories Slowed the Buildup of DNA Mutations in Mice

It is the first look at the effect across most of the genome, and it says less about human dieting than it first appears.

·2 min read
Holstein cows grazing in a lush green pasture under a clear blue sky on a sunny day.Health
Members

Bird Flu Keeps Spreading Through US Dairy Herds, but Store Milk Is Still Safe to Drink

Federal testing has found no live virus in commercial pasteurized dairy, and health officials still rate the everyday risk to the public as low, even as the number of infected herds keeps climbing.

·1 min read
Illustration of a DNA double helix beside red blood cells, one of them a crescent-shaped sickle cellLongevity & Science

A Gene-Editing Cure for Sickle Cell Now Works in the Patients Who Need It Most

The science of curing sickle cell is close to settled; whether that cure ever reaches the millions of people who have it is the question a new study begins to answer.

·4 min read
John Bissell, PhD, author of The Power of Negative Thinking: A Practical Guide to the Strength Doubt and Worry Can Give YouMental Health

John Bissell's The Power of Negative Thinking Draws on 14 Years Rescuing Failing Businesses in Portland

The author lost a company of his own when a single client went bankrupt owing him 83% of his income, then coached more than 100 owners of failing businesses between 1986 and 2000. His practical guide argues that doubt and worry, used deliberately, are better preparation than forced positivity.

·5 min read
Illustration of a GLP-1 injection pen beside an abstract rising line, showing growth over time.Health

GLP-1 Prescriptions Rise 310-Fold Among Young Children With Obesity

The drugs were developed for adults, and clinical guidelines already allow them for obesity in children as young as 8.

·3 min read
A doctor uses a stethoscope on a smiling patient in a bright room, indicating a positive medical experience.science & tech, Health
Members

Mounjaro Can Now Be Prescribed to Lower Heart Attack and Stroke Risk in Type 2 Diabetes

The FDA cleared the once-weekly injection for people with type 2 diabetes who face high cardiac risk, based on a trial that tested it against an older drug already known to protect the heart.

·1 min read
A person using contactless payment at a retail counter in Portugal wearing an apron.
Members

FDA Authorizes the JUUL2 Vaping System Four Years After Moving to Ban Juul

The clearance covers a redesigned system with optional built-in age verification, and it returns Juul to a legal market it no longer leads.

·1 min read
Athletic person performing an intense battle rope exercise in a modern gym setting.Fitness & Movement
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GLP-1 Users Are Spending More on Fitness and Less on Snacks and Restaurants

The gap runs to nearly four to one by one survey's count, but the shift is concentrated among affluent users and may not outlast their prescriptions.

·1 min read
Close-up of a healthcare worker in protective gear examining a medical vial.Longevity & Science
Members

Scientists Race to Make the First Bundibugyo Ebola Vaccine as Congo's Outbreak Grows

The outbreak is the second-largest Ebola epidemic ever recorded, caused by a strain no licensed vaccine can stop, and funders are now backing several vaccine candidates at once, including a new one from an Egyptian company.

·1 min read
Elderly man wearing eyeglasses reading documents next to a laptop at home.Health, Everyday Wellness
Members

A Lawsuit Challenges the Paywall Around the Codes on Your Medical Bill

A transparency group is suing the American Medical Association to free the CPT code set, and the outcome could change what patients can look up about their own bills.

·1 min read
Illustration of a medical perfusion machine keeping a donor liver alive and oxygenated in a glowing chamber on a clinical cartLongevity & Science

The NHS Will Fund Machines That Keep Donated Livers Alive Outside the Body

The change, recommended by NICE, should let surgeons safely use donor organs they might once have turned down, and improve the odds that a transplant works from the start.

·3 min read
A warm, candlelit setting featuring an astrology natal chart, perfect for divination themes.Mental Health, Everyday Wellness

Astrologer Nancy Volante Treats Burnout Through the Nervous System, Not the Calendar

The founder of The Whispering Soul in Ridgefield, Connecticut, a former professional dancer who ran a yoga studio for eight years, has folded 25 years of astrology study into a four-session coaching program that starts with the body.

·6 min read
World Trade Center responders in hard hats work amid twisted debris at Ground Zero after the September 11 attacksLongevity & Science

9/11 Responders With PTSD Have Older-Looking Brains

For the men and women who spent weeks in the toxic dust of Ground Zero, a new brain-imaging study suggests the hours they logged at the site may still be shaping how their minds grow old.

·4 min read
Illustration of a hospital heartbeat line turning into a circuit board with a magnifying glass over a network of nodesscience & tech
Members

Clinical AI Reaches Patients Faster Than Anyone Tracks Its Mistakes

ECRI, a national patient-safety nonprofit, is building the first healthcare-specific system to log the errors AI tools make once they are inside real patient care.

·1 min read
Illustration of a glowing DNA double helix with fine threads linking points along the strand over a dark gridscience & tech
Members

Scientists Can Now See What AI Models Learn From Raw DNA

A method called PISA traces a model's prediction at any single DNA base back to every other base behind it, exposing when the model has learned the quirks of an experiment instead of real biology.

·1 min read
Illustration of four ways cannabis is used, a rolled joint, a vape pen, two gummy edibles and a glass jar of cannabis flower, arranged on a plain surfaceEveryday Wellness

The Way You Use Cannabis, Not Just How Much, May Flag Addiction Risk

The people who blend smoking, vaping, edibles and dabbing turned up as the group most likely to meet the clinical bar for a cannabis problem.

·4 min read
A fluorescence microscopy image of cells glowing in bright magenta and white against a black background.Longevity & Science

A Hidden Molecule Stops Iron From Poisoning Our Cells

The finding, from researchers at MIT’s Whitehead Institute, reveals a surprising second role for polyamines, a class of small molecules found in every cell, and points toward new strategies against cancer and a clue to early-onset Parkinson’s disease.

·4 min read
Illustration of a focused beam of light striking a cluster of cell-like forms, with one targeted cell glowing warm amberLongevity & Science

Light Made a Cancer Drug Up to 96 Times More Potent in the Lab

In mice, the same light trigger that boosted the drug CX-5461 also set off a vaccine-like immune response against their tumors, though the approach is still years from human testing.

·4 min read